The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally

Sheba Medical Center

Status: Unknown

Conditions: Ataxia Telangiectasia

Study type: Observational

Funder types: Other

Identifiers

NCT00951886

SHEBA-08-5418-OE-CTIL

Details and patient eligibility

About

Rationale: Forced spirometry maneuvers are not routinely performed in patients with Ataxia Telangiectasia (A-T), even though they suffer from respiratory illnesses.

Objectives: To study the feasibility and validity of forced spirometry in A-T patients.

Methods: Patients will perform spirometry during clinical visits. Parameters studied will be technical quality, relation to predicted values, age, pulmonary illness, body mass index, mutational status and mutation.

Enrollment: 28 patients

Sex: All

Ages: 3 to 20 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with proven Ataxia Telangiectasia

Exclusion criteria

• inability to perform spirometry