The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer

Peking University Cancer Hospital & Institute

Status: Enrolling

Conditions: Colon Cancer

Treatments: Procedure: Beyond complete mesocolic excision surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT05859581

Colon MRI-2023-01

Details and patient eligibility

About

The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.

The main questions it aims to answer are:

• Concordance between MRI suspected RPRM positive and pathologically confirmed positive.
• Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection?

Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.

Enrollment: 29 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• primary colon adenocarcinoma confirmed by biopsy
• preoperative CT suspecting retroperitoneal resection margin (RPRM) positive
• received colon MRI scan
• underwent beyond complete mesocolic excision surgery
• sufficient clinical and pathological results

Exclusion criteria

• combined with other malignant tumors
• simultaneous distant metastasis
• definite invaded other organs or structures (T4b tumors)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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29 participants in 1 patient group

Suspected positive RPRM on MRI

Experimental group

Treatment:

Procedure: Beyond complete mesocolic excision surgery