The Value of Serum MicroRNA-21-5p and LncRNAgadd7 Expression Levels in Predicting the Severity and Prognosis of ARDS ( Acute Respiratory Distress Syndrome )

Shao Yuekai

Status: Completed

Conditions: Acute Respiratory Distress Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT06825754

KLLY-2023--198

Details and patient eligibility

About

By measuring the expression levels of MicroRNA-21-5p (miR-21-5p) and LncRNAgadd7 in the peripheral blood of ARDS patients, the study aims to explore the correlation between these levels and the severity and prognosis of ARDS.

Enrollment: 110 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥ 18 years;
2. Meets the Berlin Criteria for ARDS;
3. Diagnosed with ARDS within 48 hours;
4. Signed informed consent.

Exclusion criteria

1. Immunosuppressed patients: including those on immunosuppressive drugs, history of stem cell transplantation, etc.;
2. Patients with malignant tumors;
3. Pregnant women;
4. Patients discharged from the ICU within 48 hours;
5. History of chronic lung diseases.

Trial design

110 participants in 2 patient groups

Survival Group

Death Group