The Ventilation During In-hospital Cardiac Arrest Study (VENT-IHCA)

University of Aarhus

Status: Enrolling

Conditions: Heart Arrest; In-Hospital Cardiac Arrest; Cardiac Arrest (CA)

Treatments: Other: Positive pressure ventilation during cardiopulmonary resuscitation

Study type: Observational

Funder types: Other

Identifiers

NCT06809309

2022-0367531 (Registry Identifier)

1-16-02-301-24 (Registry Identifier)

VENT-IHCA

Details and patient eligibility

About

The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult patients.

The main questions it aims to answer are:

What ventilation volume during CPR is associated with the highest chance of return of spontaneous circulation (ROSC)? What ventilation rate during CPR is associated with the highest chance of ROSC?

Researchers will compare different levels of ventilation rates and volumes that are blindly measured during CPR to see how the observed rates and volumes are associated with survival outcomes and complications.

Enrollment: 900 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. In-hospital cardiac arrest
2. Age ≥ 18 years
3. >1minute of recorded ventilation data

Exclusion criteria

1. Documented do-not-attempt cardiopulmonary resuscitation order
2. Invasive mechanical circulatory support at the time of the cardiac arrest

Trial design

900 participants in 1 patient group

Study cohort

Description:

Adult patients (≥18 years) with in-hospital cardiac arrest receiving cardiopulmonary resuscitation. Groups will be defined based on observed distribution of ventilation parameters (ventilation rate, tidal volume and minute ventilation).

Treatment:

Other: Positive pressure ventilation during cardiopulmonary resuscitation