The Volume Effect of Hydrodissection for Carpal Tunnel Syndrome

National Taiwan University

Status: Completed

Conditions: Carpal Tunnel Syndrome

Treatments: Procedure: Dextrose 1mL injection; Procedure: Dextrose 2mL injection; Procedure: Dextrose 4mL injection

Study type: Interventional

Funder types: Other

Identifiers

NCT03598322

201711014RINA

Details and patient eligibility

About

The investigators investigated the volume effect of hydrodissection for Injection therapies in patients with Carpal Tunnel Syndrome. The investigators evaluated participants by Shear Wave Ultrasound Elastography and Artificial Intelligence Imaging Analysis

Full description

The investigators investigated the volume effect of hydrodissection for Injection therapies in patients with Carpal Tunnel Syndrome. The investigators evaluated participants by Shear Wave Ultrasound Elastography and Artificial Intelligence Imaging Analysis

Enrollment: 63 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 20-80

• Electrophysiological diagnosis of carpal tunnel syndrome

• At least one of the following two:

  1. Tenderness or numbness over median nerve innervated dermatome over 2 months
  2. Phalen test or Tinel sign or flick sign positive

Exclusion criteria

• History of wrist surgery
• Wrist trauma in recent two years
• Received wrist injection in recent three months
• History of brachial plexopathy, cervical radiculopathy or thoracic outlet syndrome
• History of DM, thyroid disorder or autoimmune disease
• Unable to cooperate with interview, examination or injection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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63 participants in 3 patient groups

Dextrose 1mL

Active Comparator group

Description:

Dextrose injection, Dextrose 1mL, active comparator

Treatment:

Procedure: Dextrose 1mL injection

Dextrose 2mL

Experimental group

Description:

Dextrose injection, Dextrose 2mL

Treatment:

Procedure: Dextrose 2mL injection

Dextrose 4mL

Experimental group

Description:

'Dextrose injection, Dextrose 4mL

Treatment:

Procedure: Dextrose 4mL injection