Therapeutic Drug Monitoring of Tacrolimus Biliary Concentrations for Liver-transplanted Patients (STABILE)

Rennes University Hospital

Status: Completed

Conditions: Biliary Concentration of Tacrolimus

Treatments: Drug: Tacrolimus

Study type: Observational

Funder types: Other

Identifiers

NCT02820259

35RC16_9755

Details and patient eligibility

About

The purpose of this study is to demonstrate that the biliary concentration of TCR is a good marker of its immunosuppressive activity.

Enrollment: 42 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (> 18 years) of both sexes,
• Candidates for liver transplantation or retransplantation, whatever the etiology and severity of the underlying disease,
• Not having expressed their opposition to participation in the study

Exclusion criteria

• Bilio-enteric anastomosis,
• Associated transplantation of another organ
• Contraindications to TCR administration
• Delayed introduction of TCR (beyond the 5th postoperative day) whatever the cause.