Therapeutic Efficacy of Categorical Language Fluency Smartphone Game Application

Seoul National University

Status

Completed

Conditions

Alzheimer's Disease

Mild Cognitive Impairment

Treatments

Device: Categorical Language Fluency Smartphone Application

Study type

Interventional

Funder types

Other

Identifiers

NCT02848404

2010-0028631

Details and patient eligibility

About

The purpose of this study is to examine therapeutic efficacy of categorical language fluency smartphone game application in mild cognitive impairment and mild Alzheimer's dementia.

Full description

The Categorical Language Fluency Smartphone Game Application was developed based on the semantic distance training, which was effective in improving categorical language fluency of mild cognitive impairment and mild Alzheimer's dementia. 10 patients with mild cognitive impairment and another 10 patients with mild Alzheimer's dementia were recruited to examine therapeutic efficacy of the application.

Enrollment

20 patients

Sex

All

Ages

55+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Aged above 55
Confirmed literacy
- Diagnosed to mild cognitive impairment by International Working Group on Mild Cognitive Impairment and Clinical Dementia Rating(CDR) of 0 or 0.5.
- Diagnosed to possible or probable Alzheimer's dementia by NINCDS-ADRDA and Clinical Dementia Rating(CDR) of 1 or below.

Exclusion criteria

Evidence of delirium, confusion
Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus
Evidence of severe cerebrovascular pathology
History of loss-of-consciousness over 1 hour due to head trauma or repetitive head trauma of mild severity
History of substance abuse or dependence such as alcohol
Presence of depressive symptoms that could influence cognitive function
Presence of medical comorbidities that could result in cognitive decline