Therapeutic Ultrasound on Renal Function

Alper Mengi

Status: Completed

Conditions: Ultrasound Therapy; Complications; Low Back Pain

Treatments: Other: physiotherapy modalities

Study type: Interventional

Funder types: Other

Identifiers

NCT03746639

2015-99-21/10

Details and patient eligibility

About

This study evaluates whether therapeutic ultrasound (TUS) treatment applied to lumbar region with chronic low back pain affect renal function.

Full description

Low back pain is a common problem and there are many treatments for chronic low back pain, including TUS. Investigators routinely observed increased blood creatinine and urea levels in some of patients who received TUS.

Half of patients will receive TUS treatment for low back pain while the other half will not receive. The patients will be evaluated at baseline and the end of the treatment . The serum creatinine, serum cystatin C, 24-hour urine creatinine, creatinine clearance, 24-hour urine microalbumin and microprotein, urine volume, and GFR will be measured at each evaluation.

Enrollment: 40 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients aged between 18 and 65 years
• with chronic mechanical low back pain for at least 3 months
• with glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m2, as calculated using the Modification of Diet in Renal Disease formula .

Exclusion criteria

• history of lumbar surgery
• having inflammatory low back pain
• having pregnancy
• having active infection
• history of malignancy
• having coagulation disorder
• having a cardiac pacemaker
• having heart failure
• having uncontrolled hypertension or hypotension
• having active psychiatric disease
• presence of skin diseases on low back pain
• taking medicines for low back pain during the physical therapy treatment (except for paracetamol)
• taking a new drug for another disease or undergoing a dose change for a drug taken during the course of physiotherapy.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

therapeutic ultrasound group

Active Comparator group

Description:

The patients will be treated with superficial heating, transcutaneous electrical nerve stimulation, exercise therapy and therapeutic ultrasound over the paravertebral low back region.

Treatment:

Other: physiotherapy modalities

therapeutic ultrasound untreated group

Other group

Description:

The patients will be treated with superficial heating, transcutaneous electrical nerve stimulation, exercise therapy over the paravertebral low back region.Therapeutic ultrasound will not be applied to this group.

Treatment:

Other: physiotherapy modalities