Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.

Goethe University

Status: Completed

Conditions: Extracorporeal Membrane Oxygenation Complication; Outcome, Fatal

Treatments: Other: Outcome

Study type: Observational

Funder types: Other

Identifiers

NCT05338593

prolonged VV-ECMO

Details and patient eligibility

About

In the context of the coronavirus (COVID-19) pandemic, healthcare systems worldwide faced an unprecedented shortage of severe ARDS. Critically affected patients were treated with veno-venous extracorporeal membrane oxygenation (VV-ECMO) for complete respiratory failure early in the pandemic. Due to a shortage of resources in the sense of terminal equipment and adequately trained personnel with appropriate expertise in many countries and regions, a strict selection of suitable patients was made. Repeatedly, it was observed that patients under VV-ECMO also needed several weeks to recover sufficiently to generate device sufficient gas exchange. Due to the scarcity of VV-ECMO resources outside of the pandemic, the question arose whether a prolonged therapy still holds a sufficient prospect of success and what the course of treatment of such patients would be like.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

veno-venous extracorporeal membrane oxygenation

Exclusion criteria

veno-arterial extracorporeal membrane oxygenation

Trial design

100 participants in 1 patient group

prolonged veno-venous extracorporeal membrane oxygenation

Description:

Critically affected patients treated with veno-venous extracorporeal membrane oxygenation (VV-ECMO). Based on severe acute respiratory distress syndrome (ARDS) and prolonged therapy for more than 2 weeks.

Treatment:

Other: Outcome