Thickness of Retinal Layers in Amblyopia

Samsung Medical Center

Status: Completed

Conditions: Amblyopia

Treatments: Other: Optical coherence tomography

Study type: Observational

Funder types: Other

Identifiers

NCT01179763

2009-12-089

Details and patient eligibility

About

The purpose of this study is to examine retinal layer thickness in amblyopia.

Full description

Amblyopia is a visual disorder characterized by a reduction of vision that cannot be immediately improved by refractive correction or accounted for by clinically determined anatomic defects of the eye or visual pathway. Evidence for direct retinal changes in eyes with amblyopia has been controversial. It has been hypothesized that amblyopia may affect the postnatal maturation of the retina including the postnatal reduction of retinal ganglion cells. However, although some studies have found incrased retinal nerve fiber layer thickness in amblyopic eyes, others have found no significant differences. This sutdy will examine the retinal layer thickness in amblyopia and compare the retinal layer thickness between amblyopic eyes and nonamblyopic fellow eyes.

Enrollment: 22 patients

Sex: All

Ages: 4 to 19 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Amblyopia

Exclusion criteria

• Other retinal disease
• Anisometropia
• Neurologic abnormalities

Trial design

22 participants in 1 patient group

Retinal layer thickness analysis

Description:

Optical coherence tomography will be conducted to analyze retinal layer thickness (safe examination)

Treatment:

Other: Optical coherence tomography