Thoracic Epidural Versus General Anesthesia for Laparoscopic Cholecystectomy

Armed Forces Hospital, Pakistan

Status: Completed

Conditions: General Anesthesia; Epidural Anesthesia

Treatments: Drug: general anesthesia effect on heart rate in Laparoscopic Cholecystectomy; Drug: Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine)

Study type: Interventional

Funder types: Other

Identifiers

NCT04721054

104589

Details and patient eligibility

About

Eighty two patients planned to undergo elective laparoscopic cholecystectomy were divided into two groups, T and G, randomly. In Group T all patients underwent laparoscopic cholecystectomy under thoracic epidural anesthesia with 12mlof 0.25% bupivacaine and 1% lignocaine plain whereas in group G all patients underwent surgery under general anesthesia. Intra-operative heart rate, mean arterial pressure (MAP) and post operative opioid consumption in first 24hrs were recorded as primary outcomes whereas presence or absence of respiratory complication and duration of hospital stay as secondary outcome.

Enrollment: 82 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. patients having ASA statusI-III
2. age more than 18 years,
3. both genders
4. planned to undergo laparoscopic cholecystectomy

Exclusion criteria

1. Patients who did not give consent,
2. Allergic to local anesthetic
3. Hemodynamically unstable,
4. Pregnant, full stomach patients

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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82 participants in 2 patient groups

group receiving thoracic epidural anesthesia

Active Comparator group

Treatment:

Drug: Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine)

group receiving thoracic general anesthesia

Active Comparator group

Treatment:

Drug: general anesthesia effect on heart rate in Laparoscopic Cholecystectomy