Thoracic Paravertebral Block : Effect on Acute Pain and Chronic Pain of Hepatectomy With Right J-shape Subcostal Incision

Cui Xulei

Status: Completed

Conditions: Nerve Block; Hepatectomy; Analgesia

Treatments: Procedure: single-injection TPVB + continuous TPVB; Device: Philip CX50 Ultrasound Scanner; Drug: Morphine given as IPCA; Drug: continuously infusion of ropivacaine; Drug: single dose ropivacaine; Device: PAJUNK Contiplex S Catheter

Study type: Interventional

Funder types: Other

Identifiers

NCT02817321

cuixulei2

Details and patient eligibility

About

This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. single-injection TPVB +continuous(pulsatile infusion) TPVB and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing hepatectomy with right J-shape subcostal incision.

Enrollment: 76 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-70 yrs
• American Society of Anesthesiologists physical statusⅠ-Ⅲ
• Undergo hepatectomy with J-shape subcostal incision
• Informed consent

Exclusion criteria

• A known allergy to the drugs being used
• Coagulopathy, on anticoagulants
• Analgesics intake, history of substance abuse
• Participating in the investigation of another experimental agent
• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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76 participants in 2 patient groups

Single-injection TPVB +continuous TPVB

Experimental group

Description:

Single-injection of TPVB is given preoperatively followed with continuous infusion+ postoperative IPCA.

Treatment:

Drug: continuously infusion of ropivacaine

Drug: single dose ropivacaine

Procedure: single-injection TPVB + continuous TPVB

Drug: Morphine given as IPCA

Device: Philip CX50 Ultrasound Scanner

Device: PAJUNK Contiplex S Catheter

IPCA

Active Comparator group

Description:

postoperative IPCA is given alone

Treatment:

Drug: Morphine given as IPCA