Thoracic Paravertebral Blocks Using a Combination of Ropivacaine and Dexmedetomidine

China Medical University, China

Status and phase: Withdrawn; Phase 4

Conditions: Thoracic Paravertebral Blocks

Treatments: Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT03677115

201707158

Details and patient eligibility

About

The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration.

Full description

The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration. The effects of dexmedetomidine have only been compared at lower doses. This trial examined the effect of greater dose of dexmedetomidine on thoracic paravertebral block analgesia duration.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients were included in the study if they were ethnic Chinese,
• American Society of Anesthesiologists (ASA) physical status I or II,
• candidates for general anesthesia undergoing thoracic surgery

Exclusion criteria

• Patients were excluded if they do not want to cooperate with the test,
• had a history of radial artery puncture or coronary artery bypass grafting,
• had acute vessel trauma,or had been diagnosed with Raynaud' disease,
• had suffered from mental or neurological disorders

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

dexmedetomidine group

Experimental group

Description:

a combination of ropivacaine and dexmedetomidine

Treatment:

Drug: Dexmedetomidine