Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients

N

Nazmy Edward Seif

Status

Completed

Conditions

Lung Diseases
Nephrectomy
Anesthesia

Treatments

Procedure: Thoracic Epidural Anesthesia
Drug: Dexmedetomidine
Drug: Fentanyl
Drug: Bupivacaine 0.5% (isobaric)
Procedure: Thoracic Spinal Anesthesia
Drug: Bupivacaine 0.5% (hyperbaric)

Study type

Interventional

Funder types

Other

Identifiers

NCT03324490
TSEANORLDP60

Details and patient eligibility

About

Patients with respiratory disease have an increased risk of developing complications perioperatively. The use of regional anesthesia decreases this risk with better postoperative outcome. The aim of this study is to compare the safety and efficacy of thoracic spinal versus thoracic epidural anesthesia for open nephrectomy in patients with obstructive/restrictive lung disease.

Enrollment

60 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • ASA class II or III
  • Mild to moderate obstructive or restrictive lung disease
  • Open nephrectomy candidate patients

Exclusion criteria

  • Any condition contra-indicating regional anesthesia
  • Allergic to any of the drugs used during the procedure

Trial design

60 participants in 2 patient groups

TSA group
Active Comparator group
Description:
Thoracic Spinal Anesthesia; Bupivacaine 0.5% (hyperbaric) 7.5mg, Fentanyl 25 µg & Dexmedetomidine 5 µg by intrathecal injection
Treatment:
Drug: Bupivacaine 0.5% (hyperbaric)
Procedure: Thoracic Spinal Anesthesia
Drug: Fentanyl
Drug: Dexmedetomidine
TEA group
Active Comparator group
Description:
Thoracic Epidural Anesthesia; Bupivacaine 0.5% (isobaric) 25-50 mg & Fentanyl 10-20 µg by epidural injection
Treatment:
Drug: Bupivacaine 0.5% (isobaric)
Drug: Fentanyl
Procedure: Thoracic Epidural Anesthesia

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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