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Three-Dimensional Vascular Reconstruction of the Pancreas on Multidetector Computed Tomography Images and Its Impact on Patients Undergoing Pancreaticoduodenectomy

I

Institute of Liver and Biliary Sciences, India

Status

Unknown

Conditions

Pancreaticoduodenectomy

Treatments

Procedure: Pancreaticoduodenectomy

Study type

Observational

Funder types

Other

Identifiers

NCT05389917
IEC/2022/92/MA10

Details and patient eligibility

About

Three-Dimensional Vascular Reconstruction of the Pancreas on Multi detector Computed Tomography images and its impact on patients undergoing Pancreatoduodenectomy - A Prospective Observational Study IPDA is difficult to identify in pre op in routine CECT images IPDA is difficult to identify in intra op Identification of those major blood vessels (SMA, MCA, Left Renal vein) that lie around the IPDA and then to measure the distances between these major vessels and the IPDA, helps to determine the location of the IPDA

Full description

Pancreaticoduodenectomy (PD) is a complex surgical procedure performed for benign and malignant indications .

Vascular anatomy of the pancreatic head, is important in multiple aspects

  • Classical arterial anatomy is observed in 55-79% of cases
  • Arterial Variation is observed in around 25-30% of cases
  • Relationship of the tumor to the blood vessels determines the resectability of tumor The presence of anatomical variations may increase the risk of complications through
  • direct (bleeding due to intraoperative vessel injury)
  • indirect (postoperative ischemia of tissues and anastomotic leakage) Preoperative understanding of the vascular anatomy of the pancreatic head is important in order to reduce intraoperative bleeding.
  • IPDA is difficult to identify in pre op in routine CECT images. It is identified in only 20% of patients.
  • IPDA is difficult to identify in intra op because- It generally originates from the posterior wall of superior mesenteric artery (SMA).The origin of IPDA frequently varies, which makes it difficult to identify in some patients. It is surrounded by dense lymphovascular tissue, which makes it difficult to identify IPDA during surgery.

IPDA can be identified in up to 86% of the time using 3D MDCT . Identification of those major blood vessels (SMA, MCA, Left Renal vein) that lie around the IPDA and then to measure the distances between these major vessels and the IPDA, helps to determine the location of the IPDA.

In the existing studies, they have not defined the impact of identifying IPDA on intra operative parameters ( Operative time, Blood loss) These studies have not used uniform landmarks in the identification of IPDA

Enrollment

25 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

• Consecutive Patients undergoing pancreaticoduodenectomy during the study period at ILBS

Exclusion criteria

  • If surgery is not proceeded for any cause like Presence of metastasis, Unreconstructable portal or SMV involvement , SMA involvement of >180 degree
  • Refusal for consent

Trial design

25 participants in 1 patient group

Consecutive adult patients undergoing pancreaticoduodenectomy
Description:
All the consecutive patients who undergo pancreaticoduodenectomy will be recruited into the study after obtaining informed consent
Treatment:
Procedure: Pancreaticoduodenectomy

Trial contacts and locations

0

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Central trial contact

Manoj Kumar YL, MBBS, MS; Piyush Kumar Sinha, MBBS,MS,MCh

Data sourced from clinicaltrials.gov

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