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Stage IIIA non-small cell lung cancers comprising a mediastinal ganglionic invasion N2 account for 20 to 30% of the NSCLCs. They are almost always potentially resectable, but the results obtained by surgery alone or surgery followed by chemotherapy (CT) and/or radiotherapy (RT) are insufficient. The neoadjuvant approach was tested, in randomized tests of exclusive CT, or in noncomparative tests of RT-CT.
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These results justify the choice of the study design currently suggested, testing the preoperative feasibility
The results obtained, in terms of feasibility and toxicity, will make it possible to select the optimal diagrams for a phase III study.
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120 participants in 3 patient groups
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Data sourced from clinicaltrials.gov
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