Thrive, a Computerized Cognitive Behavior Therapy Program to Treat Depression

Montana State University

Status: Completed

Conditions: Depressive Symptoms

Treatments: Behavioral: Thrive

Study type: Interventional

Funder types: Other

Identifiers

NCT03244878

MS033017-FC

Details and patient eligibility

About

This study evaluates a culturally-modified version of Thrive, a computerized Cognitive Behavior Therapy program to treat depressive symptoms, syndromes, and disorders among rural Montanans. Study participants will be randomized to either a wait-list treatment as usual or the Thrive program. After 8 weeks, the wait-list group will then receive Thrive. The primary assessment measure is the Patient Health Questionnaire-9.

Full description

Montana ranks high among states on mental health disorder prevalence and low on access to mental health care. It has the highest suicide rate in the nation. Of Montana's 56 counties, 10 are classified as rural and 45 as frontier, accentuating distance challenges in accessing care. New treatment delivery modalities are needed to complement, supplement and augment traditional mental health care. With increase in access to the Internet, computer-administered Cognitive Behavior Therapy (cCBT) programs have emerged as viable approaches to effective treatment of depression.

Thrive is an interactive cCBT program with a heavy emphasis on video rather than text content that appears to improve participant engagement, a shortcoming seen in prior cCBT programs.

The goal of this project is to conduct a randomized wait-list controlled of Thrive to determine its effectiveness in reducing depressive symptom severity among Montanans, many of whom have few or no other options for mental health treatment.

Enrollment: 464 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged 18 years or older
• Baseline PHQ-9 score of 5 or greater
• Montana resident
• Regular access to broadband internet (streaming capability)

Exclusion criteria

• No broadband internet access
• Aged 17 years or younger
• Does not have Montana residency
• Baseline PHQ-9 score of < 5

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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464 participants in 2 patient groups

Intervention - Thrive program

Experimental group

Description:

Participants will receive access to the Thrive program for 8 weeks

Treatment:

Behavioral: Thrive

Wait-list Control

No Intervention group

Description:

Participants will have no access to the Thrive program for 8 weeks upon enrollment. They will receive a link to the NIMH website to read about information on depression.