Thrombin Generation and Gestational Outcome

HaEmek Medical Center, Israel

Status: Completed

Conditions: Thrombophilia

Study type: Observational

Funder types: Other

Identifiers

NCT02139670

thrombin generation- pregnancy

Details and patient eligibility

About

In total 120 pregnant women's with history of recurrent miscarriages, are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). The relation between pregnancy outcome and thrombin measurements will be determined

Enrollment: 29 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age > 18
• signed inform consent
• first trimester
• two early miscarriages(before week 10) or one later abortions (after week 10)

Exclusion criteria

• Chronic treatment with aspirin or other anticoagulants

Trial design

29 participants in 1 patient group

pregnant womens