Thromboelastography During Surgery for Malignant Pleural Mesothelioma

Mass General Brigham

Status: Unknown

Conditions: Coagulopathy; Mesothelioma

Treatments: Procedure: Blood draw for TEG analysis

Study type: Observational

Funder types: Other

Identifiers

NCT01912547

2013P000653

Details and patient eligibility

About

Surgery for malignant pleural mesothelioma is complex and prolonged, and may involve significant blood loss with considerable blood and product transfusion. Thromboelastography (TEG) is a global assay of coagulation that uses whole blood to produce a tracing that records kinetic changes in clot formation. This study aims provide a better understanding of the coagulation profile of these patients, and will form the basis of a TEG-based transfusion algorithm for future surgeries for mesothelioma.

Full description

Thromboelastography can provide more in-depth and quicker analysis of the complex coagulation processes during surgery

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult male or female patients undergoing elective surgery for malignant pleural mesothelioma

Exclusion criteria

• Unwilling or unable to provide consent
• History of bleeding disorder
• On medications that may affect hemostasis

Trial design

100 participants in 1 patient group

Blood draw for TEG analysis

Description:

TEG analysis of blood from patients at different points in time

Treatment:

Procedure: Blood draw for TEG analysis