Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis (STRATEGIC)

Vanderbilt University Medical Center

Status: Withdrawn

Conditions: GastroIntestinal Bleeding; Coagulopathy; Cirrhosis, Liver

Treatments: Diagnostic Test: Thromboelastography

Study type: Interventional

Funder types: Other

Identifiers

NCT05583539

221098

Details and patient eligibility

About

The goal of this clinical trial is to compare resuscitation strategies in patients with cirrhosis and gastrointestinal bleeding. The main question it aims to answer is whether thromboelastography guided resuscitation decreased the amount of fresh frozen plasma patients receive. Patients will receive blood products guided by thromboelastography in the intervention group. Researchers will compare the patients who undergo thromboelastography guided resuscitation to those who receive usual care to see which strategy leads to the use of less blood products, specifically less fresh frozen plasma.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged 18 years or older
• Octreotide order placed for the indication of upper gastrointestinal bleeding in cirrhosis

Exclusion criteria

• None

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

Usual Care

No Intervention group

Description:

Patients will receive usual care at the discretion of their providers.

Thromboelastography guided resuscitation

Experimental group

Description:

Patients will undergo thromboelastography testing that will be used by primary providers to guide blood product resuscitation.

Treatment:

Diagnostic Test: Thromboelastography