Thromboelastography in Non-elective Cesarean Delivery

Stanford University

Status: Completed

Conditions: Bleeding

Study type: Observational

Funder types: Other

Identifiers

NCT01514591

SU-08162011-8270

IRB 22205 (Other Identifier)

Details and patient eligibility

About

The purpose of the study is to assess the coagulation changes that occur in laboring patients undergoing non-elective (intrapartum)Cesarean delivery using thromboelastography (TEG). We will compare coagulation data to assess potential coagulation changes associated with hemoglobin changes before and after surgery, and related to estimated blood loss.

Full description

The purpose of the study is to assess the coagulation changes that occur in laboring patients undergoing non-elective (intrapartum)Cesarean delivery using thromboelastography (TEG). TEG is a point- of-care device which measures the viscoelastic properties of clot formation. This device can provide rapid and detailed information about coagulation changes in the perioperative period. We will compare coagulation data collected from the study to assess potential coagulation changes associated with Hemoglobin changes before and after surgery, and related to estimated blood loss.

Enrollment: 33 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Obstetric in-patients
• Laboring patients with Epidurals for Labor Analgesia going for non-elective Cesarean
• Patients of all ethnic backgrounds will be included
• Singleton pregnancy
• ASA 1 or 2

Exclusion criteria

• Patients with underlying coagulation disorders.
• Patients with thrombocytopenia (platelet count <100).
• Patients with pregnancy-induced hypertension, pre-eclampsia.
• Patients requiring the following medications prior to surgery: NSAIDS, aspirin, anticoagulants.
• Patients requiring elective Cesarean delivery.
• Patients with significant obstetric or medical disease.
• No patients <18 years of age will be recruited.

Trial design

33 participants in 1 patient group

Non-elective Cesarean Delivery

Description:

We will only enroll patients undergoing non-elective CS with an 'epidural top-up' for surgical anesthesia. By definition, our study will only apply to laboring women with working labor epidurals (which were provided for labor analgesia).