Thromboelastography to Study Burn Coagulopathy

Francesco Egro

Status: Not yet enrolling

Conditions: Coagulation, Blood; Burn

Treatments: Diagnostic Test: Thromboelastography

Study type: Interventional

Funder types: Other

Identifiers

NCT06879509

STUDY23120009

Details and patient eligibility

About

This pilot study examines the use of thromboelastography (TEG), a specialized blood test, to evaluate clotting abnormalities in burn patients. The study aims to understand how burn injuries impact the body's ability to form and break down blood clots over time. Specifically, the investigators will research whether the percentage of total body surface area burned (%TBSA) is associated with changes in blood clotting, track the evolution of clotting patterns during the first four weeks following a burn injury, and explore whether these changes can predict recovery or complications. By providing new insights into clotting dynamics in burn patients, the study seeks to improve diagnostic methods, enhance monitoring strategies, and guide treatments to optimize patient care and outcomes.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted with acute burn injuries
• Aged 18 years and older
• Provided consent to participate in the study

Exclusion criteria

• Patients with a history of venous thromboembolism or hyper/hypocoagulopathy

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Burn Thromboelastography Group

Experimental group

Description:

Overall study population (all participants are in the same group). See eligibility for further details.

Treatment:

Diagnostic Test: Thromboelastography