Thrombolytic Care During Inter-hospital Transfer

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University of Iowa

Status

Completed

Conditions

Stroke

Treatments

Drug: Tissue Plasminogen Activator

Study type

Observational

Funder types

Other

Identifiers

NCT02752256
IRB:201507803

Details and patient eligibility

About

Evaluation of ischemic stroke patients receiving tissue plasminogen activator (rtPA) during air ambulance transfer

Full description

The purpose of our study is to evaluate the effect of air ambulance transport on patients presenting with an ischemic stroke and receive tissue plasminogen activator (rtPA). Primary outcome will be the evaluation of air ambulance transfer and if it leads to protocol violations or significant delays in therapy. Protocol violations include inaccurate dosing or preparation at the outside hospital, uncontrolled blood pressure before and during the flight, unnecessary medication administration before and during the flight and adverse events (intracranial bleeding, allergic reaction) associated with transfer process. Additional evaluation will include the effects of vibration of the air ambulance and its effects on the lytic activity of rtPA. rtPA is not supposed to be significantly agitated after it is prepared in solution and there is significant vibration and agitation during air ambulance transfer.

Enrollment

76 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients who received tissue plasminogen activator for acute ischemic stroke
  • presented directly to comprehensive stroke center or were transferred by our air ambulance service

Exclusion criteria

Transferred by another air ambulance service or ground ambulance

Trial design

76 participants in 2 patient groups

Intervention/Transfer
Description:
Patients who are transferred via air ambulance to a comprehensive stroke center
Treatment:
Drug: Tissue Plasminogen Activator
Control
Description:
Patients presenting directly to the comprehensive stroke center
Treatment:
Drug: Tissue Plasminogen Activator

Trial documents
1

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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