Thrombotic Effects of Yellowstripe Scad

University of Putra Malaysia (UPM)

Status: Completed

Conditions: Thrombosis

Treatments: Other: Salmon; Other: YSS

Study type: Interventional

Funder types: Other

Identifiers

NCT03251014

FPSK(FR16)P005 (Other Identifier)

06-01-04-SF2310

NMRR-16-2693-32300. (Registry Identifier)

Details and patient eligibility

About

The study aimed to determine the thrombotic effects of YSS compared with salmon among healthy overweight subjects. It hypothesized that YSS may result significant, favorable thrombotic effects and the effects may be similar with salmon.

Full description

The project was a randomized, two-period, crossover trial with 8-week treatment periods and 8-week washout period. A total of 50 healthy overweight adults were recruited among staff and students in UPM. All the subjects were randomized into two groups. Each group was served with either cooked YSS (~265 g/ day) or salmon (~246 g/day) thrice per week. Blood and urine samples were collected for laboratory assessment.

Enrollment: 50 patients

Sex: All

Ages: 21 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Malaysian
• Overweight participants (BMI 23-27.4 kg/m2)

Exclusion criteria

• Regular use of fish oil supplements during the last one month
• Regular consumption of fish twice or more per week
• Vegetarian who excluded all meat, fish, and poultry from their diet
• Diagnosed with cardiovascular disease, haemostasis disorder, inflammatory disease, diabetes mellitus, hypertension, or other significant medical history that may prohibits the participation
• Receiving warfarin or aspirin treatment, or medication to lower serum lipids, blood pressure, and inflammation
• Women who are menopause, pregnant or lactating

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

YSS/salmon group

Experimental group

Description:

YSS followed by salmon

Treatment:

Other: YSS

Other: Salmon

Salmon/YSS group

Experimental group

Description:

Salmon followed by YSS

Treatment:

Other: YSS

Other: Salmon