Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics and Cost-utility

Töölö Hospital

Status: Enrolling

Conditions: Thumb Osteoarthritis; Quality of Life; Arthritis; Arthropathy

Treatments: Procedure: Trapeziectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04826380

3163/2020

Details and patient eligibility

About

A project aiming to promote evidence based practice when treating thumb basal joint (CMC I) arthritis. We will aim to: 1) provide the minimal clinical difference of two general outcome instruments, 2) evaluate the association between pre-operative anxiety and/or depression and outcomes following trapeziectomy, 3) evaluate the effect of trapziectomy on carpal cinematics, 4) determine the cost-utility-ratio of trapeziectomy

Enrollment: 150 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eaton-Glickel >2 arhritis
• Symptom duration >3 months
• Pain VAS >30mm
• No significant comorbidities, ASA I-II
• Fluent in Finnish language

Exclusion criteria

• Eaton-Glickel <2
• Duration of symptoms <3 months
• VAS <30mm
• ASA >II
• Inflammatory joint disease
• Systemic corticosteroid or immunomodulatory medication
• Upper limb symptoms not explained with CMC I artritis
• Heavy smoking (> 20 cigarettes per day)
• Alcohol or drug abuse
• Neurological condition affecting upper limb function
• Other ipsilateral upper limb condition requiring surgery

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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150 participants in 2 patient groups

Trapeziectomy

Other group

Description:

Simple trapeziectomy for treating CMC I arthritis

Treatment:

Procedure: Trapeziectomy

Conservative

No Intervention group

Description:

Conservative measures (e.g. splint, NSAID, activation modification) for treating CMC I arthritis