Thumb vs Great Toe Recovery

Mayo Clinic

Status: Completed

Conditions: Residual Neuromuscular Blockade

Treatments: Device: TetraGraph

Study type: Interventional

Funder types: Other

Identifiers

NCT04312256

19-011705

Details and patient eligibility

About

Researches are comparing the accuracy of measuring muscle relaxation in the thumb versus the great toe.

Enrollment: 81 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > or = 18 years old
• Patients willing to participate and provide an informed consent
• Patients undergoing an elective surgical procedure that requires use of non-depolarizing NMBA agents administered intraoperatively.
• Patients with planned administration of sugammadex as a neuromuscular blocking reversal agent.

Exclusion criteria

• Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
• Patients with systemic neuromuscular diseases such as myasthenia gravis
• Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
• Patients having surgery that would involve prepping the arm or leg into the sterile field

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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81 participants in 1 patient group

Dominant Hand and great toe

Experimental group

Description:

Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the dominant hand and great toe.

Treatment:

Device: TetraGraph