Thyroid Gland Dysfunction and Vitamin D Polymorphism in Keratoconus

Mansoura University

Status

Completed

Conditions

Keratoconus

Treatments

Diagnostic Test: ELISA,DNA extraction

Study type

Observational

Funder types

Other

Identifiers

NCT05073601

R.21.01.1157.R1

Details and patient eligibility

About

This prospective study the thyroid gland dysfunction and vitamin D receptor polymorphism in keratoconus patients

Full description

This is a prospective observational study in which blood samples are collected from keratoconus patients looking for thyroid dysfunction and vitamin D levels in the serum and assessing the Vitamin D receptor polymorphism in comparison to healthy control.

Enrollment

262 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

keratoconus patients without previously diagnosed thyroid disorder in comparison to healthy control without known systemic disease and with normal cornea who were selected from candidates of refractive surgery with normal topography

Exclusion criteria

patients who could not provide informed consent or the necessary samples for any reason, patients with associated other ophthalmic pathologies or systemic disorders were excluded from the study