Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients

M.D. Anderson Cancer Center

Status: Completed

Conditions: Fever; Febrile Neutropenia

Treatments: Other: Survey Administration; Other: Interview

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT03968328

2015-0272 (Other Identifier)

NCI-2019-02655 (Registry Identifier)

Details and patient eligibility

About

This trial uses an interview and a survey to gather information from cancer patients about the onset of their fever and the administration of antibiotics. Collecting information from patients may help doctors to assess the relationship between time to antibiotic administration and inhospital cause specific death, intensive care unit admission, hospital length of stay, and positive blood cultures.

Full description

PRIMARY OBJECTIVES:

I. To assess the prognostic value of the length of time between the time onset of fever and first antibiotic administration on cause specific 14 day mortality rate.

SECONDARY OBJECTIVES:

I. To assess the associations of the length of time between the time onset of fever and first antibiotic administration with intensive care unit (ICU) admission, ICU length of stay, length of hospitalization and percentage of patients with positive blood cultures.

OUTLINE:

Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.

Enrollment: 315 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

IInclusion criteria:

--> 18 years of age

• Temperature above 38.0 documented
• ANC< 500/mm3

Exclusion Criteria:

--Age <18

Trial design

315 participants in 1 patient group

Observational (interview, survey)

Description:

Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.

Treatment:

Other: Survey Administration

Other: Interview