Time - Related Cuff Pressure and Volume of the Laryngeal Tube With the Use of Nitrous Oxide

Prince of Songkla University

Status: Completed

Conditions: Adult Disease

Treatments: Device: laryngeal tube (VBM Medizintechnik)

Study type: Observational

Funder types: Other

Identifiers

NCT01346384

LT-N2O

Details and patient eligibility

About

The purpose of this study is to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.

Full description

Background : The laryngeal tube airway (LT) is an extraglottic airway device with a proximal and distal conical cuff designed to secure a patient's airway during either spontaneous breathing or controlled ventilation. Application of this device with the use of N2O may be related to the ischemic change of the oropharyngeal mucosa. The objective of this study was to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.

Methods : Seventy-five patients were studied with the use of LT size 4. N2O (66%) and isoflurane were used to maintain anesthesia. Initial intracuff pressure and volume were recorded for airway sealing during ventilation. Time-course changes of the intracuff pressure followed by recording every 10 min. If the intracuff pressure reached 100 cmH2O, the cuff was deflated to the initial intracuff pressure and the volume of deflated air and postoperative airway complications were recorded.

Enrollment: 75 patients

Sex: All

Ages: 15 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologist physical status I or II
• Undergoing elective orthopedic surgery and surgery of breast under general anesthesia with an expected duration of 60 min or more

Exclusion criteria

• Height was < 155 or >180 cm (for the use of laryngeal tube size 4)
• Body mass index ≥35 kg/m2
• Preexisting laryngotracheal disease
• Risk of pulmonary aspiration of gastric contents.

Trial design

75 participants in 1 patient group

intracuff pressure N2O

Description:

measured intracuff pressure of LT with N2o during operative period

Treatment:

Device: laryngeal tube (VBM Medizintechnik)