Time-restricted Eating and High Intensity Interval Training Among Women

Norwegian University of Science and Technology

Status: Completed

Conditions: Obesity; Endocrine

Treatments: Behavioral: High Intensity Interval Training; Behavioral: Time-Restricted Eating

Study type: Interventional

Funder types: Other

Identifiers

NCT04019860

2019/851

285171 (Other Identifier)

Details and patient eligibility

About

This project will determine the independent and combined effects of high intensity interval training and time-restricted eating on blood sugar regulation among women in reproductive-age who have overweight or obesity. The intervention period will be seven weeks. Before and after the intervention, blood sugar regulation, body composition and physical fitness will be measured and compared between groups who are doing either high intensity interval training, time-restricted eating, both high intensity interval training and time-restricted eating, or who are in a control group. Physical activity, sleep quality, continuous glucose monitoring, adherence to the interventions and hunger/satiety will also be measured.

Full description

In a follow-up study, we will invite randomized participants to come in for new assessments of physical fitness, body composition and fasting blood samples, and they will be asked to complete questionnaires about adherence to the interventions two years after intervention-end. The first participants will come in to the laboratory for the two-year follow up in November 2021.

Enrollment: 131 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• body mass index ≥ 27 kg/cm2,
• able to walk on a treadmill or ride a bike for at least 60 min.

Exclusion criteria

• Pregnancy, lactation within 24 weeks of study commencement
• known cardiovascular disease
• type 1 or 2 diabetes
• currently taking hypertension or glucose- or lipid-lowering medication
• habitual eating window < 12 hours
• performing high intensity training more than once a week
• body mass variations > 4 kg three months prior to study commencement
• shift work that includes night shifts.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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131 participants in 4 patient groups

High Intensity Interval Training

Experimental group

Description:

High intensity interval training for seven weeks. Three weekly, supervised training sessions.

Treatment:

Behavioral: High Intensity Interval Training

Time-Restricted Eating

Experimental group

Description:

Time-restricted eating for seven weeks. Maximal daily eating window of 10 hours.

Treatment:

Behavioral: Time-Restricted Eating

High Intensity Interval Training & Time-Restricted Eating

Experimental group

Treatment:

Behavioral: Time-Restricted Eating

Behavioral: High Intensity Interval Training

Control

No Intervention group

Description:

Will be given information about the recommended level of physical activity for health benefits and a healthy diet.