Time Restricted Fasting and Aerobic Exercise Interventions Among Sedentary Adults

Guangzhou Sport University

Status: Completed

Conditions: Sedentary; Aging

Treatments: Behavioral: Time Restricted Fasting; Behavioral: Aerobic Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05865639

20230411

Details and patient eligibility

About

This project will determine the independent and combined effects of aerobic exercise and time restricted fasting on cardiovascular risks among sedentary middle-aged and elderly adults. The online intervention period will be eight weeks. Before and after the intervention, arterial stiffness, cardiac autonomic nervous, body composition, glucolipid metabolism, sleep and eating habits, inflammatory reaction, sedentary behavior and physical activity level will be measured and compared between groups who are doing either aerobic exercise, time restricted fasting, both aerobic exercise and time restricted fasting, or who are in a control group. Adverse reaction, sleep and eating quality, life quality and adherence to the interventions and hunger/satiety will also be measured.

Enrollment: 56 patients

Sex: All

Ages: 45 to 69 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: 45-69 years old Sedentary time ≥8 hours per day
• Irregular exercise habits
• No drugs affecting the outcome index were taken
• No history of serious diseases
• Sign the subject informed consent and agree to participate in this experiment.

Exclusion criteria

• The range of body weight change in the last three months is more than 3kg
• People taking weight-loss drugs
• Participate in other experimenters 5 months before the experiment
• Unable to adjust and follow the intervention schedule.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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56 participants in 4 patient groups

Aerobic Exercise

Experimental group

Description:

Aerobic exercise for eight weeks. Three weekly, supervised training sessions.

Treatment:

Behavioral: Aerobic Exercise

Time Restricted Fasting

Experimental group

Description:

Time restricted fasting for eight weeks. Maximal daily eating window of 8 hours.

Treatment:

Behavioral: Time Restricted Fasting

Aerobic exercise & Time Restricted Fasting

Experimental group

Treatment:

Behavioral: Time Restricted Fasting

Behavioral: Aerobic Exercise

Control

No Intervention group

Description:

Will be given information about the recommended level of physical activity for health benefits and a healthy diet.