Timing and Resistance Exercise: Impact on Eating and Metabolism

National Taiwan Normal University

Status: Not yet enrolling

Conditions: Appetitive Behavior; Circadian Rhythm; Energy Balance; Food Reward

Treatments: Other: The exercise in morning; Other: The exercise in evening

Study type: Interventional

Funder types: Other

Identifiers

NCT06549322

202401HM008

Details and patient eligibility

About

Exercise timing (morning or evening) for optimal weight control is a research topic urgently addressed by scholars in the relevant field. Due to the better control of energy metabolism and physical activity levels in the morning, existing research on resistance exercise and eating behavior primarily focuses on experiments conducted in the morning, with only one study in the afternoon. No research has yet compared the potential differences between morning and evening resistance exercise. A one-year study aims to investigate the impact of morning and evening resistance exercise on physiological metabolism and eating behavior. Eighteen healthy male participants will be randomly assigned to a crossover design study, including AM exercise, PM exercise, and control (rest condition) trials. Variables including subjective appetite, appetite hormones (ghrelin, peptide YY), food preferences, ad libitum eating, dietary records, energy expenditure, and PBMCs circadian rhythm genes will be measured. This preliminary study through a multidimensional observation, the results will contribute to understanding the potential differences and mechanisms of morning and evening resistance exercise on physiological metabolism and eating behavior. In practical applications, conducting resistance exercise in the evening or at night aligns better with current lifestyles. The findings of this study can support the optimization of exercise benefits by validating the choice of exercise timing.

Enrollment: 18 estimated patients

Sex: Male

Ages: 20 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: 20-30
• weight stable for at least 6 months

Exclusion criteria

• Obesity (BMI > 30 kg/m² or body fat percentage > 25%)
• Hypertension (blood pressure over 140/90 mmHg)
• Heart disease
• Cancer
• Liver or kidney diseases
• Any other conditions that could potentially influence the study's outcomes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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18 participants in 3 patient groups

The exercise in morning

Experimental group

Description:

Resistance exercises are in the following order: squat, bench press, deadlift. Each exercise consists of 3 sets with 7 repetitions, using a load of 70% 1RM with 60 sec of rest between sets.

Treatment:

Other: The exercise in morning

The exercise in evening

Experimental group

Description:

Resistance exercises are in the following order: squat, bench press, deadlift. Each exercise consists of 3 sets with 7 repetitions, using a load of 70% 1RM with 60 sec of rest between sets.

Treatment:

Other: The exercise in evening

The control in all day

No Intervention group

Description:

Sit and rest in the morning and evening during the day.