Timing of Prophylactic Antibiotics for Cesarean Sections

Medical University of South Carolina (MUSC)

Status: Completed

Conditions: Endometritis; Wound Infection

Treatments: Drug: Cefazolin

Study type: Interventional

Funder types: Other

Identifiers

NCT00330278

HR # 11120

Details and patient eligibility

About

This is a randomized, double-blinded placebo controlled trial of cefazolin timing before cesarean section fo infection prophylaxis. Subjects are randomized to cefazolin either 30 minutes prior to skin incision or at time of cord-clamping. Primary outcome is infectious morbidity including wound infections and endometritis.

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Pregnant 24-43 weeks gestation > 18 years old Requiring cesarean section -

Exclusion criteria

Receiving antibiotics < 18 years old Allergy to cefazolin

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind