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Timing of Rocuronium After Induction With Propofol on Temporal Summation of Pain

W

Wonkwang University Hospital

Status

Completed

Conditions

Gynecological Disorder

Treatments

Other: The difference of the timing of rocuronium administration after propofol injection

Study type

Interventional

Funder types

Other

Identifiers

NCT04547608
WonkwangUH7

Details and patient eligibility

About

Temporal summation of pain, which is defined as the perception of increasingly greater pain evoked by repetitive painful stimuli, is highly variable between individuals. This study aimed to determine the impact of the timing of rocuronium after induction with propofol on temporal summation of pain in gynecologic laparoscopic surgery.

Enrollment

100 patients

Sex

Female

Ages

19 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Elective gynecologic laparoscopic surgery
  • American Society of Anesthesiologists' physical status class) I-II

Exclusion criteria

  • Menopause (to exclude the hormonal effect on pain)
  • Patients who had muscular, cardiovascular, hepatic or kidney disorders and patients with a history of medication who would affect muscle relaxants were excluded from this study.
  • Patients with difficult venous access on forearm, a known allergy to propofol or rocuronium, chronic pain, pregnancy, and those who had received analgesics or sedatives within the previous 24 hours, were excluded from the study.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

100 participants in 2 patient groups

group PRi
Other group
Description:
received immediate injection of rocuronium after propofol administration,
Treatment:
Other: The difference of the timing of rocuronium administration after propofol injection
group PRd
Other group
Description:
rocuronium injection when bispectral index score became below 60 after propofol administration
Treatment:
Other: The difference of the timing of rocuronium administration after propofol injection

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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