Timing of Treatment Completion in Staged Selective Laser Trabeculoplasty (SLT): Early vs. Late Completion

Queen's University

Status and phase: Terminated; Phase 3

Conditions: Glaucoma

Treatments: Procedure: Selective laser trabeculoplasty - late completion; Procedure: selective laser trabeculoplasty - early completion

Study type: Interventional

Funder types: Other

Identifiers

NCT00551395

RC-1

Details and patient eligibility

About

This study will evaluate the effect of the timing of treatment completion in two-staged selective laser trabeculoplasty therapy on intraocular pressure lowering effect.

Full description

SLT therapy is used as an IOP lowering agent in patients with glaucoma. It is unknown whether the timing of a 2-staged approach to the laser therapy will result in better IOP lowering effect.

This study will evaluate the timing (early vs. late completion of SLT therapy) and determined the IOP lowering effect following the interventions.

Arm 1: Early Completion SLT

180 degrees of SLT on Day 1, 180 degrees of SLT on the other 180 degrees on Day 2

Arm 2: Late Completion SLT

180 degrees of SLT on Day 1, 180 degrees of SLT on the other 180 degrees at the 1 month follow up visit.

Primary Outcome: IOP (mmHg).

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age
• primary open angle glaucoma or pseudoexfoliation glaucoma

Exclusion criteria

• Unable to give informed consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

SLT Early Completion (Arm 1)

Experimental group

Description:

Intervention: 180 degrees of laser on Day 1, 180 degrees of laser on the other 180 degree on Day 2

Treatment:

Procedure: selective laser trabeculoplasty - early completion

SLT Late Completion (Arm 2)

Active Comparator group

Description:

Intervention: 180 degrees of laser on Day 1, 180 degrees of laser on the other 180 degrees at 1 month follow up appointment.

Treatment:

Procedure: Selective laser trabeculoplasty - late completion