(TIMP-2)x(IGFPB7) to Predict Acute Kidney Injury (AKI) in Aortic Surgery (TIGER)

Jörg Schefold

Status: Completed

Conditions: Renal Failure; Dialysis; Acute Kidney Injury; Biomarker; Aortic Surgery

Treatments: Other: does not apply

Study type: Observational

Funder types: Other

Identifiers

NCT03469765

TIGER

Details and patient eligibility

About

New biomarkers that predict the development of renal dysfunction in patients with aortic surgery are urgently needed. The investigators investigate whether urinary (TIMP-2)x(IGFBP7) predicts postoperative Acute Kidney Injury and/or need for Renal Replacement Therapy (RRT) in patients after aortic surgery (including EVAR).

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients in need of emergency or elective abdominal aortic surgery (infra- or suprarenal clamping or EVAR) are eligible for study inclusion.

Exclusion criteria

• Patients unable to give informed consent
• Age < 18
• Patients not speaking German or French.

Trial design

100 participants in 1 patient group

Group of patients after aortic surgery

Description:

with subanalysis of patients with/without supra-/infrarenal surgery

Treatment:

Other: does not apply