Tissue Composition of Newborn Infants of Obese and Lean Mothers

Hvidovre University Hospital

Status: Completed

Conditions: Obesity

Treatments: Behavioral: Exercise; Behavioral: diet

Study type: Interventional

Funder types: Other

Identifiers

NCT01235676

DEXA-2650

Details and patient eligibility

About

0-hypothesis: the tissue composition of newborn infants is not modified by lifestyle intervention during pregnancy

Full description

Obese pregnant women (BMI > 30) are randomized to exercise, diet or control (1:1:1) in order to reduce weight gain during pregnancy. Shortly after birth, tissue composition will be measured (DEXA)in 200 infants (65 from each group). The amount of fat tissue is subsequently analyzed between the groups and compared to results from another 65 infants of lean mothers

Enrollment: 270 patients

Sex: All

Ages: Under 3 days old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Healthy term neonates Informed and written consent from both parents -

Exclusion criteria

Sick or preterm infants No consent

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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270 participants in 2 patient groups

Diet

Experimental group

Description:

Calorie restriction to reduce weight gain

Treatment:

Behavioral: diet

Exercise

Experimental group

Description:

Exercise to reduce weight gain

Treatment:

Behavioral: Exercise