Tissue Oxygen Index and Pulsatility Index in Orthopedic Surgery: a NIRS and TCD Pilot Trial

Medical University of Vienna

Status: Completed

Conditions: Cerebral Microemboli

Treatments: Device: Transcranial Doppler Ultrasound, DWL Doppler BoxX

Study type: Observational

Funder types: Other

Identifiers

NCT02340416

1633/2013

Details and patient eligibility

About

Cerebral microemboli (ME) are frequently generated during major orthopaedic surgery. The primary objective of this study was applying novel transcranial Doppler (TCD) ultrasound software algorithm to quantify (ME load/15 minutes) and qualify (particulate vs. gaseous) ME, detected as high-intensity transient signals (HITS) in both middle cerebral arteries (MCAs) before and after orthopaedic surgery.

Enrollment: 50 patients

Sex: All

Ages: 50 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hip prosthesis
• knee prosthesis
• shoulder prosthesis
• spine surgery

Exclusion criteria

• severe valvular heart defect
• acute neurological disorder