Tissue Penetration of Antibiotics in Obesity

The Washington University

Status: Completed

Conditions: Obesity

Study type: Observational

Funder types: Other

Identifiers

NCT00752908

070678

Details and patient eligibility

About

The purpose of this study is to evaluate cefoxitin pharmacokinetics in obese surgical patients.

Enrollment: 27 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI <25 and >40
• Scheduled for elective abdominal or pelvic surgery
• Surgical plan for intraoperative cefoxitin prophylaxis
• Able to provide informed consent

Exclusion criteria

• Allergy to Cefoxitin
• Renal or Hepatic insufficiency

Trial design

27 participants in 2 patient groups

Obese patients

Description:

Obese patients

Normal weight patients and volunteers

Description:

Normal weight patients and volunteers