Tissue Sample Collection From Patients With Fanconi Anemia

OHSU Knight Cancer Institute

Status: Completed

Conditions: Fanconi Anemia; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific

Treatments: Other: biologic sample preservation procedure; Procedure: biopsy

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00899522

OSHU-CR00003822

IRB00001100

CDR0000445453 (Other Identifier)

OHSU-IRB00001100

P30CA069533 (U.S. NIH Grant/Contract)

OHSU-HEM-03022-LX

Details and patient eligibility

About

RATIONALE: Collecting and storing samples of tumor tissue from patients with Fanconi anemia to test in the laboratory may help the study of cancer in the future.

PURPOSE: This laboratory study is collecting and storing tumor tissue samples from patients with Fanconi anemia.

Full description

OBJECTIVES:

• Acquire rare solid tumor samples from patients with Fanconi anemia in order to create a Fanconi Anemia Cell Repository at the Oregon Health and Science University Cancer Institute.
• Study repository tissue using a variety of molecular methods, including gene microarrays.
• Develop cancer cell lines that are publicly available from tissue archived from patients with Fanconi anemia.

OUTLINE: Tumor biopsies are collected from patients with Fanconi anemia and archived for future molecular studies, cell line generation, and general usage by the research community at large. Medical information about the patient's cancer is also archived.

PROJECTED ACCRUAL: Not specified.

Enrollment: 8 patients

Sex: All

Ages: 1 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Confirmed Fanconi anemia
• Confirmed malignant solid tumor
• Biopsy of tumor tissue available

PATIENT CHARACTERISTICS:

• Not specified

PRIOR CONCURRENT THERAPY:

• Not specified