TME Alteration in HER2 Positive Breast Cancer

Seoul National University

Status: Active, not recruiting

Conditions: Chemotherapy Effect; Breast Cancer; HER2-positive Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT06533670

2402-110-1514

Details and patient eligibility

About

Evaluate for changes in the tumor microenvironment before/during neoadjuvant chemotherapy and after treatment in patients diagnosed with HER2-positive advanced breast cancer and receiving neoadjuvant cancer therapy and surgery for curative purposes.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria i. Adult patients over 18 years of age ii. Patients undergoing curative treatment including neoadjuvant chemotherapy after confirmation of breast cancer without distant metastases iii. Clinical T stage II-IV patients iv. HER2 positive breast cancer patients

Exclusion criteria If you have other comorbidities that, according to the researcher's judgment, may affect the results of the study