TMQLB Versus TPVB for Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery

Cui Xulei

Status: Terminated

Conditions: Nerve Block, Nephrectomy, Analgesia

Treatments: Procedure: TMQLB group 2; Procedure: TMQLB group 1; Procedure: TPVB

Study type: Interventional

Funder types: Other

Identifiers

NCT03414281

cuixulei5

Details and patient eligibility

About

This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and quality of recovery in laparoscopic renal surgery compared with thoracic paravertebral block (TPVB).

Enrollment: 30 patients

Sex: All

Ages: 17 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 17~80 years of age;
• American Society of Anesthesiologists physical status I-III;
• undergoing laparoscopic nephrectomy.

Exclusion criteria

• have a known allergy to the anesthetics being used;
• infection at injection site
• coagulopathy or history of anticoagulants use
• chronic analgesics consumption or history of substance abuse
• inability to properly describe postoperative pain or recovery to investigators (e.g., language barrier, neuropsychiatric disorder).

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 3 patient groups

TMQLB group 1

Experimental group

Description:

0.4ml/kg ropivacaine is injected into the interfascial plane between the psoas major and quadratus lumborum muscle using TMQLB approach.

Treatment:

Procedure: TMQLB group 1

TMQLB group 2

Experimental group

Description:

0.6ml/kg ropivacaine is injected into the interfascial plane between the psoas major and quadratus lumborum muscle using TMQLB approach.

Treatment:

Procedure: TMQLB group 2

TPVB group

Active Comparator group

Description:

0.4ml/kg ropivacaine is injected into the thoracic paravertebral space (T10) using TPVB approach.

Treatment:

Procedure: TPVB