TMS and Body Image Treatment for Anorexia Nervosa

Region Östergötland

Status: Enrolling

Conditions: Anorexia Nervosa

Treatments: Behavioral: Body Image Intervention; Device: Transcranial magnetic stimulation; Behavioral: Treatment as usual

Study type: Interventional

Funder types: Other

Identifiers

NCT04213820

2019-02821

Details and patient eligibility

About

To evaluate if TMS together with a body image intervention is an efficacious treatment for anorexia nervosa compared to treatment as usual.

Enrollment: 40 estimated patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being enrolled as a patient at the eating disorder unit of the Child and adolescent psychiatric clinic and Psychiatric clinic in Linköping
• Having a DSM-5 diagnosis of anorexia nervosa, atypical anorexia (restrictive type)
• Being at least 18 years of age
• Having a BMI of 20 or under.
• Being free of psychotropic medications or on stable (at least three months on the same dose) medication.

Exclusion criteria

• Clinical diagnosis of schizophrenia or psychotic disorder
• Clinical diagnosis of bipolar disorder
• Alcohol/drug dependence
• Ongoing treatment with antipsychotics or tricyclic antidepressants
• Previous severe head injury
• Birth before 33 weeks of gestation
• Hearing impairment
• Earlier epilepsy or seizures of other causes
• Having severe claustrophobia
• Being pregnant
• Having a cognitive disability

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 3 patient groups

Treatment as usual

Active Comparator group

Description:

Participants will receive treatment as usual at the eating disorder unit at the Child and adolescent psychiatric clinic and at the Psychiatric clinic during 4 weeks.

Treatment:

Behavioral: Treatment as usual

TMS and body image intervention

Experimental group

Description:

Participants will receive TMS and a body image intervention daily 5 times/week during 4 weeks

Treatment:

Behavioral: Body Image Intervention

Device: Transcranial magnetic stimulation

sham TMS and body image intervention

Sham Comparator group

Description:

Participants will receive sham TMS and a body image intervention Daily 5 times/week during 4 weeks

Treatment:

Behavioral: Body Image Intervention