To Better Understand the Most Important Factors for Patients When They Decide on the Type of Treatment They Receive for Muscle Invasive Bladder Cancer (MIBC).

King's College London

Status: Enrolling

Conditions: Patient Preference; Muscle Invasive Bladder Cancer; Patient Satisfaction; Surgery; Sexual Wellbeing

Treatments: Other: Discrete Choice Experiment (DCE) Patients DCE Questionnaire; Other: Semi-Structured Interview Patients Interview

Study type: Observational

Funder types: Other

Identifiers

NCT05236218

PTPDCE

Details and patient eligibility

About

Through our study, we aim to understand the most important factors for patients when they decide on the type of treatment they receive for MIBC. Our study consists of a discrete choice experiment (DCE): a type of questionnaire used to elicit preferences in the absence of data. DCEs are frequently used in oncological research to elicit preferences from participants without directly asking them to state their preferred options. Participants undertaking our DCE questionnaire will presented with a series of alternative hypothetical scenarios containing several variables or "attributes" (5), each of which may have a number of variations or "levels".

Full description

The study will be conducted using validated and established protocols for undertaking DCEs. A literature review was undertaken to assess what the most important considerations where for patients when making decisions about the treatment they receive for MIBC. Using this literature search as a starting point, discussion groups with relevant healthcare professionals and service users were undertaken to decide on the final attribute and levels for the questions. Five attributes were selected through an iterative process - Body image, Life expectancy, Side-effects from treatment, Living as bladder cancer survivor, and Sexual wellbeing

The study is divided into three stages:

1. Interviews with experienced healthcare professionals and service users to finalise attributes and levels to be used for the questionnaire
2. A representative sample of patients (~10) will be asked to complete the questionnaire in addition to a brief unstructured interview to assess understanding (e.g. readability and ease of completing the questionnaire)
3. Necessary changes based on feedback from the pilot study will be applied before the main study is carried out

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with MIBC cancer and currently undergoing treatment or have previously completed treatment for MIBC

Exclusion criteria

• Any of other type of bladder cancer (unknown, metastatic, or non muscle invasive bladder cancer)

Trial design

60 participants in 2 patient groups

Pilot study (n = 10)

Description:

10 participants will be recruited to complete the questionnaire (version 1). A research assistant will be present to help support them /answer any questions around the format. Readability and comprehension will be noted. Any changes (if needed) can be implemented to its format before the main data collection.

Treatment:

Other: Semi-Structured Interview Patients Interview

Discrete Choice Experiment Questionnaire (n = 50)

Description:

Discrete Choice Experiment (DCE) Patients

Treatment:

Other: Discrete Choice Experiment (DCE) Patients DCE Questionnaire