To Evaluate the Correlation Between the Results of Specific Gene Testing and the Efficacy of Targeted Therapy in Patients With NSCLC

Hunan Province Tumor Hospital

Status: Completed

Conditions: Non Small Cell Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05805267

CONFIDENCE II

Details and patient eligibility

About

Evaluated the correlation between the qualitative test results of Xiamen Aide the gene test specified by the test reagent and the efficacy of relevant targeted drugs in patients with non-small cell lung cancery, and the research data is used to support the registration and marketing of the assessment reagent

Enrollment: 130 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1)≥18;
• 2. advanced non-small cell lung cancer confirmed by histopathology;
• 3. Patients with NSCLC who have previously or are taking gefitinib (first-line therapy) or osimertinib (post-TKI resistance) or crizotinib monotherapy, and the response to treatment can be assessed;
• 4. Have sufficient FFPE tissue samples within 5 years: 5 large specimens/case; There were 10 puncture specimens/case

Exclusion criteria

• 1. Combination therapy with chemotherapy/radiotherapy/other targeted drugs/immunotherapy drugs;
• 2)Maintenance therapy if the disease does not progress after treatment with other antitumor methods