To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations

Shinshu University

Status: Enrolling

Conditions: Osteoarthritis of Multiple Joints; Progression of Rheumatoid Arthritis

Treatments: Procedure: The examinations for bones in joints of OA and RA patients

Study type: Observational

Funder types: Other

Identifiers

NCT02327650

OA RA Bone Study

Details and patient eligibility

About

Generally, osteoarthris (OA) is considered as primarily cartilage disease. However, as we and others have previously reported, a portion of OA might be caused primarily by bone alterations. In this study, we prospectively and retrospectively show that the bone altertations may affect OA primarily in all of the joints.

In addition, rheumatoid arthritis (RA) is a joint disease when immune system attacks synovium. Joint destruction occurrs continuously if suitable treatment is not performed. The etiology of RA is still largely unknown. As with OA, RA can be primarily damaged in bone, instead of cartilage. Here we prospectively and retrospectively show that the bone altertations may affect RA primarily in all of the joints.

Enrollment: 200 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• RA and/or OA

Exclusion criteria

• N/A

Trial design

200 participants in 1 patient group

RA and OA

Description:

Every 2 or 3 months, plain radiograph, blood and urinary tests, and MRI are performed in the painful joints of RA.

Treatment:

Procedure: The examinations for bones in joints of OA and RA patients