Tobramycin Exposure From Active Calcium Sulfate Bone Graft Substitute

Lausanne University Hospital (CHUV)

Status: Completed

Conditions: Orthopedic Operations

Treatments: Drug: tobramycin

Study type: Observational

Funder types: Other

Identifiers

NCT01938417

Tobramycin cast

Details and patient eligibility

About

This study aimed to assess the systemic absorption and disposition of tobramycin in patients treated with a tobramycin-laden bone graft substitute (Osteoset® T).

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (> or =18 years old) patients
• Treatment with Osteoset® T

Exclusion criteria

• Intravenous tobramycin

Trial design

12 participants in 1 patient group

adult patients treated with Osteoset® T (tobramycin sulfate)

Description:

10 g or 20 g of Osteoset® T

Treatment:

Drug: tobramycin