Tolerance to Light for Patients Suffering From Keratitis (EBLOUI)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Keratitis

Treatments: Device: Light exposure

Study type: Interventional

Funder types: Other

Identifiers

NCT03586505

1708072

2017-A03451-52 (Other Identifier)

Details and patient eligibility

About

In order to develop an innovative device to study infectious keratitis, we need to illuminate the cornea of patients suffering from an infectious keratitis with red or near-infrared light. Because of technical reasons the shortest possible wavelength (red) presents advantages.

Full description

The aim of this preliminary study is to measure the maximal intensity tolerated during illumination with 6 wavelength corresponding : 2 red, 2 far red and 1 near infrared lights in order to determine the shortest wavelength well tolerated by patients, in comparison with the standard blue light illumination.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Social security insurance
• Suspected infectious keratitis (clinically defined. No lab testing required)
• Signed informed consent

Exclusion criteria

• Major Blepharospasm
• Aphakia (absence of lens)
• Pregnant woman
• Nursing mother

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Light exposure

Experimental group

Description:

The keratitis eye of the patient is exposed to 6 lights with increasing intensity according to a constant speed. The patients switch off the light when the discomfort is too elevated

Treatment:

Device: Light exposure