Tools for Reducing Inequity in Acute Leukemia (TRIAL): Beta Testing

Dana-Farber Cancer Institute

Status: Enrolling

Conditions: Acute Leukemia; Leukemia

Treatments: Behavioral: TRIAL Web-Based Application

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06907797

K08CA273043 (U.S. NIH Grant/Contract)

24-698

Details and patient eligibility

About

This study aims to test the Tools for Reducing Inequity in Acute Leukemia (TRIAL) web-based application that is designed to support participants with acute leukemia by providing information and resources about leukemia and clinical trial participation.

Full description

The goal of this single-arm pilot study is to test the TRIAL web application which is designed to reduce inequity in clinical trial enrollment among participants with acute leukemia. The application aims to facilitate access to clinical trials and reduce barriers for underrepresented groups.

The research study procedures include screening for eligibility and questionnaires.

Participation in this research study is expected to last about 14 weeks.

It is expected about 75 people will participate in this study.

The National Cancer Institute (NCI) and American Society of Clinical Oncology (ASCO) are providing funding for this study.

Enrollment: 75 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 or older
• English speaking
• Ability to understand and willingness to sign written informed consent
• Clinical suspicion of acute leukemia
• Admitted to DFCI-affiliated inpatient unit

Exclusion criteria

• Cognitive impairment rendering the individual unable to participate in beta testing

  • This will be assessed by focused chart review and consultation with the patients' inpatient care team.

• The following populations will be excluded: adults unable to consent, individuals who are not yet adults (infants, children, teenagers <18 years old), prisoners.

• Inability to participate in in-person application testing.

• Patients who participated in alpha-testing through protocol 23-404 (Appendix A)

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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75 participants in 1 patient group

TRIAL Web-Based Application

Experimental group

Description:

Enrolled participants will complete: * Baseline visit and questionnaires * Access to web application over the course of 14 days. * End of study questionnaires * 12 participants will take part in semi-structured interviews with study staff which will be audio recorded.

Treatment:

Behavioral: TRIAL Web-Based Application