Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata

Aswan University Hospital

Status: Completed

Conditions: Alopecia Areata

Treatments: Diagnostic Test: vitamin D3 level; Device: Narrow Band UVB; Drug: Calcipotriol

Study type: Interventional

Funder types: Other

Identifiers

NCT03847441

Alopecia Calcipotiol

Details and patient eligibility

About

Alopecia Areata is a common condition. This study investigated the efficacy of calcipotriol versus Narrow Band Ultraviolet B in treatment of Alopecia areata and their effects on serum vitamin D3 levels.

Enrollment: 60 patients

Sex: All

Ages: 14 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Alopecia Areata of scalp

Exclusion criteria

Other causes of alopecias including scarring alopecia, androgenic alopecia, telogen effluvium autoimmune diseases, pregnant and lactating females

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 4 patient groups, including a placebo group

Group I

Active Comparator group

Treatment:

Diagnostic Test: vitamin D3 level

Drug: Calcipotriol

Group II

Active Comparator group

Treatment:

Diagnostic Test: vitamin D3 level

Device: Narrow Band UVB

Group III

Active Comparator group

Treatment:

Diagnostic Test: vitamin D3 level

Drug: Calcipotriol

Device: Narrow Band UVB

Group IV

Placebo Comparator group

Treatment:

Diagnostic Test: vitamin D3 level